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Since the e-cigarette trend is only about 10 years old, it may take decades for reliable data to be collected and analyzed and for currently unknown harms to be understood

These findings suggest that e-cigarette use fosters a distinct periodontal microbial environment, positioning it as an intermediate state between that of traditional smokers and nonsmokers, while also presenting unique oral health challenges [84]

Some makers of vape products and liquids attempted to avoid FDA rules for e-cigarettes by now using lab-made nicotine

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